Laboratoř růstových regulátorů
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Pracovníci
- Mgr Tomáš Vlčko
vedoucí skupinyvedoucí vědecký pracovník
- Prof. Mgr. Ondřej Novák Ph.D.
zástupce vedoucího laboratořevědecký pracovník
- Prof. ing. Miroslav Strnad CSc.
vedoucí vědecký pracovník
vědecký pracovník
- RNDr. Martin Fellner Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- doc. Mgr. Danuše Tarkowská Ph.D.
vědecký asistent
odborný pracovník
- Mgr. Ota Blahoušek
- Ing. Věra Doleželová
- Mgr. Pavel Jaworek Ph.D.
- Ivan Petřík
postdoktorand
sekretářka-asistentka
- Jitka Hansgutová DiS.
údržba
Výzkumné projekty
- Biosyntéza a signalizace u giberelinů - identifikace nových cílů pro regulaci růstu rostlin , GA ČR , Peter Hedden
- Syntéza nových brassinosteroidů a studium jejich interakce s rostlinnými a živočišnými receptory , GA ČR , Miroslav Kvasnica
- Cílené metabolické profilování rostlinných růstových regulátorů , MŠMT , Ondřej Novák
Publikace
2010
- JOURNAL OF BIOLOGICAL CHEMISTRY 285 23369-23384 2010 (External fulltext)
- MOLECULAR PLANT-MICROBE INTERACTIONS 23 1164-1174 2010 (External fulltext)
- ANALYTICAL AND BIOANALYTICAL CHEMISTRY 398 2071-2080 2010 (External fulltext)
- ANALYTICA CHIMICA ACTA 680 86-91 2010 (External fulltext)
- JOURNAL OF PHYCOLOGY 46 1198–1205 2010 (External fulltext)
- PLANT CELL 22 3905-3920 2010 (External fulltext)
- PLANT JOURNAL 61 467–481 2010 (External fulltext)
- MOLECULES 15 9214-9229 2010 (External fulltext)
- BIOLOGIA PLANTARUM 54(3): 483-487, 2010 Fulltext: PDF link pouze na intranetu
2009
- ARCHIVES OF PHARMACAL RESEARCH 32 [1] 75-78 2009