Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Workers
head of the laboratorysenior scientist
- Prof. Mgr. Ondřej Novák Ph.D.
deputy head of the laboratoryscientist
- Prof. ing. Miroslav Strnad CSc.
senior scientist
scientist
- RNDr. Martin Fellner Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- doc. Mgr. Danuše Tarkowská Ph.D.
scientific assistant
graduated technical assistant
- Mgr. Ota Blahoušek
- Ing. Věra Doleželová
- Ivan Petřík
assistant
- Jitka Hansgutová DiS.
- Mgr. Pavel Jaworek Ph.D.
maintenance
Research projects
Publications
2016
- PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES 113 11016-11021 2016 Fulltext: public PDF link
2015
-
In vitro antioxidant activity and phenolic composition of Georgian, Central and West European wines.JOURNAL OF FOOD COMPOSITION AND ANALYSIS 41 113-121 2015
- FOOD and AGRICULTURAL IMMUNOLOGY 26 [4] 504–511 2015
- INTERNATIONAL JOURNAL OF FOOD PROPERTIES 18 1471–1477 2015
- PLANT GROWTH REGULATION 75 483-492 2015 (External fulltext)
- JOURNAL OF EXPERIMENTAL BOTANY 66 6927–6943 2015 (External fulltext)
- MOLECULAR CELL 57 984-994 2015 Fulltext: public PDF link
- PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES 112 291-296 2015 Fulltext: public PDF link
- PLANT CELL 27 1955-1967 2015 Fulltext: public PDF link
- PLOS ONE 10 (2) e0117793 2015 (External fulltext)